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CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Ki values of 40 nM and 30 nM, respectively. It does not inhibit or only weakly inhibits other protein kinases like Plk1 and RSK2. CC260 is suitable for research in cell energy metabolism, diabetes, and cancer.
Enhances insulin-induced Akt phosphorylation at both Thr-308 and Ser-473
Suppresses S6K phosphorylation (Thr-389) by mTORC1
Significantly increases phosphorylation of acetyl-CoA carboxylase (ACC) in a dose-dependent manner
Reduces the ability of BT474 cells to survive serum starvation
Increases glycolytic ATP production in BT474 cells
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Annexin A8 is a recombinant human annexin family protein provided as a His-tagged recombinant product for research applications. It is expressed in E. coli and supplied in small-scale quantities for biochemical and cell biology studies, with an approximate molecular weight of 38 kDa.
recombinant human protein, suitable for research use only.
n-terminal 6xHis tag to facilitate purification and detection.
expressed in Escherichia coli expression system.
molecular weight approximately 38 kDa.
available in small research sizes, including a 50 μg quantity.
recommended for biochemical and cell biology assays.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Polyoxyethylene (100) stearyl ether is a nonionic surfactant and emulsifying agent with an average number-average molecular weight (Mn) of approximately 4,670. It is used as a solubilizer and formulation aid in laboratory and industrial formulations, supplied as a white to off-white solid with supporting SDS and datasheet documentation available.
Nonionic surfactant and emulsifier.
High average molecular weight (Mn ≈4,670) for improved solubilization.
White to off-white solid form for convenient handling and storage.
Suitable for formulation, emulsification, and solubilization applications.
Safety and technical documentation available (SDS and datasheet).
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Recombinant human Annexin A8 protein, His-tagged, provided as a purified recombinant protein of approximately 38 kDa for laboratory research use. The product is not classified as hazardous and should be handled by qualified personnel; storage and handling instructions are provided in the Certificate of Analysis.
His-tagged recombinant human protein.
Approximate molecular weight 38 kDa.
Intended for laboratory research use only.
Not classified as a hazardous substance or mixture.
Store tightly sealed in a cool, well-ventilated area; avoid direct sunlight.
Follow Certificate of Analysis for recommended storage conditions.
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(E/Z)-ZINC09659342 is a small-molecule research reagent that inhibits the Lbc-RhoA protein-protein interaction. It is supplied as a solid powder and as DMSO solutions for laboratory use; analytical documents (datasheet, COA, SDS) are available. For research use only; not for human or clinical applications.
Inhibits Lbc-RhoA interaction for studies of RhoA signaling.
High purity (approximately 99.7%).
Molecular weight 440.37; formula C23H15F3N2O4.
Available as solid quantities (5 mg-100 mg) and 10 mM DMSO solution.
Datasheet, certificate of analysis, and safety data sheet available.
Intended for laboratory research; not for clinical use.
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